Factors for tumor progression in patients with skull base chordoma

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Factors for tumor progression in patients with skull base chordoma

Skull base chordoma is a rare and fatal disease, recurrence of which is inevitable, albeit variable. We aimed to investigate the clinicopathologic features of disease progression, identify prognostic factors, and construct a nomogram for predicting progression in individual patients. Data of 229 patients with skull base chordoma treated by one institution between 2005 and 2014 were retrieved an...

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An intradural skull base chordoma presenting with acute intratumoral hemorrhage.

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MR Imaging Grading System for Skull Base Chordoma.

BACKGROUND AND PURPOSE Skull base chordoma has been widely studied in recent years, however, imaging characteristics of this tumor have not been well elaborated. The purpose of this study was to establish an MR imaging grading system for skull base chordoma. MATERIALS AND METHODS In this study, 156 patients with skull base chordomas were retrospectively assessed. Tumor-to-pons signal intensit...

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Genomic and transcriptomic characterization of skull base chordoma

Skull base chordoma is a primary rare malignant bone-origin tumor showing relatively slow growth pattern and locally destructive lesions, which can only be characterized by histologic components. There is no available prognostic or therapeutic biomarker to predict clinical outcome or treatment response and the molecular mechanisms underlying chordoma development still remain unexplored. Therefo...

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Diffusion-weighted MRI: distinction of skull base chordoma from chondrosarcoma.

BACKGROUND AND PURPOSE Chordoma and chondrosarcoma of the skull base are rare tumors with overlapping presentations and anatomic imaging features but different prognoses. We hypothesized that these tumors might be distinguished by using diffusion-weighted MR imaging. MATERIALS AND METHODS We retrospectively reviewed 19 patients with pathologically confirmed chordoma or chondrosarcoma who unde...

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ژورنال

عنوان ژورنال: Cancer Medicine

سال: 2016

ISSN: 2045-7634,2045-7634

DOI: 10.1002/cam4.834